Antipsychotic drugs and risk of venous thromboembolism: nested case-control study

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Antipsychotic drugs and risk of venous thromboembolism: nested case-control study.

OBJECTIVE To determine whether antipsychotic drugs are associated with an increased risk of venous thromboembolism, and to examine risks by type of antipsychotic, potency, and dose. DESIGN Population based nested case-control study. SETTING The UK QResearch primary care database. PARTICIPANTS Patients (cases) with a first ever record of venous thromboembolism between 1 January 1996 and 1 ...

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ABO blood groups and risk of venous thromboembolism during pregnancy and the puerperium. A population-based, nested case-control study.

OBJECTIVES To examine possible associations of ABO blood types with the risk of venous thromboembolism (VTE) in pregnancy and the puerperium. PATIENTS AND METHODS We conducted a nested case-control study within a cohort of 71,729 women who gave birth to 126,783 children in the North Jutland County, Denmark, from 1980 to 2001. We identified 129 cases with VTE in pregnancy (n = 61) or the puerp...

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Risk of venous thromboembolism due to antipsychotic drug therapy.

An increasing number of reports suggest a link between venous thromboembolism (VTE) and the use of antipsychotics. To better understand this association the available body of evidence has been critically scrutinised. Relevant articles were identified in the databases Scopus and PubMed. Several observational studies using different methodologies show an increased risk of VTE in psychiatric patie...

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Antipsychotic drug exposure and risk of pulmonary embolism: a population-based, nested case–control study

BACKGROUND Only three observational studies investigated whether exposure to antipsychotics is associated with an increased risk of pulmonary embolism, with conflicting results. This study was therefore carried out to establish the risk of pulmonary embolism associated with antipsychotic drugs, and to ascertain the risk associated with first- and second-generation antipsychotic drugs, and with ...

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ژورنال

عنوان ژورنال: BMJ

سال: 2010

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.c4245